解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:Clinical reasoning in Neurology is based on general associations which help to deduce the site of the lesion. However, even "golden principles" may occasionally be deceptive. Here, we describe the case of subacute flaccid tetraparesis due to motor cortical lesions. To our knowledge, this is the first report ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-017-0814-5
更新日期:2017-02-10 00:00:00
abstract:BACKGROUND:Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a clinically heterogeneous disorder characterized by epileptic seizures, psychosis, dyskinesia, consciousness impairments, and autonomic instability. Symptoms are always various. Sometimes it presents in milder or incomplete forms. We report 4 cases ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0787-9
更新日期:2017-01-05 00:00:00
abstract:BACKGROUND:Heterogeneous disease trajectories of mild cognitive impairment (MCI) and dementia are frequently encountered in clinical practice, but there is still insufficient knowledge to understand the reasons and mechanisms causing this heterogeneity. In addition to correlates of the disorder, patient characteristics...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0750-9
更新日期:2016-11-25 00:00:00
abstract:BACKGROUND:The AD etiology is yet not properly known. Interactions among environmental factors, multiple susceptibility genes and aging, contribute to AD. This study investigates the factors that play role in causing AD and how changes in cellular pathways contribute to AD. METHODS:PUBMED database, MEDLINE database an...
journal_title:BMC neurology
pub_type: 杂志文章,评审
doi:10.1186/s12883-016-0765-2
更新日期:2016-11-22 00:00:00
abstract:BACKGROUND:Despite substantial research into the topic and valiant surgical efforts, reconstruction of peripheral nerve injury remains a challenging surgery. This study was conducted to evaluate the effectiveness of axonal regeneration of a transected sciatic nerve through a vein conduit containing degenerated skeletal...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0768-z
更新日期:2016-11-22 00:00:00
abstract:BACKGROUND:A description of the complexity of the process of self-management and the way stroke survivors give meaning to their process of self-management post-stroke is lacking. This study explores how stroke survivors managed their lives, gave meaning to their self-management post-stroke and how this evolved over tim...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0739-4
更新日期:2016-11-15 00:00:00
abstract:BACKGROUND:The number of patients suffering post-stroke seizure after ischemic stroke (PSSi) is quite considerable, especially because ischemic stroke is more prevalent than hemorrhage in the general population. This study aimed to determine the predicting factors for seizure recurrence in ischemic stroke survivors and...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0729-6
更新日期:2016-11-05 00:00:00
abstract:BACKGROUND:Assessing primary rehabilitation needs in patients with acquired brain injury is a challenge due to case complexity and the heterogeneity of symptoms after brain injury. The Rehabilitation Complexity Scale-Extended (RCS-E) is an instrument used in assessment of rehabilitation complexity in patients with seve...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0728-7
更新日期:2016-10-21 00:00:00
abstract:BACKGROUND:In children with cerebral palsy (CP), stiffness, caused by contractile and non-contractile structures, can influence motor performance. This study sought to determine whether the nerve mobility had a relevant impact on motor performance in children with CP. We hypothesized that a positive Straight Leg Raise ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0715-z
更新日期:2016-10-07 00:00:00
abstract:BACKGROUND:Past studies found that cerebral developmental venous anomaly (DVA) is often concurrent with cavernous malformation (CM). But the reason of the concurrency remains unknown. The purpose of this study was to confirm whether angioarchitectural factors relate to the concurrence and which angioarchitectural facto...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0691-3
更新日期:2016-09-22 00:00:00
abstract:BACKGROUND:Autosomal recessive cerebellar ataxias (ARCA) are a group of neurodegenerative disorders characterized by early onset of gait impairment, disturbed limb coordination, dysarthria, and eye movement abnormalities, most likely due to the degeneration of cerebellum, brainstem, and spinal cord. Despite of the rari...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0696-y
更新日期:2016-09-20 00:00:00
abstract:BACKGROUND:Alternating hemiplegia of childhood (AHC) is a rare neurological disorder that manifests recurrent attacks of hemiplegia, oculogyric, and choreoathetotic involuntary movements. De novo mutations in ATP1A3 cause three types of neurological diseases: AHC; rapid-onset dystonia-Parkinsonism (RDP); and cerebellar...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0680-6
更新日期:2016-09-15 00:00:00
abstract:BACKGROUND:Amongst Sardinians the human leukocyte antigen (HLA) DRB1-DQB1 haplotypes *15:02-*06:01, *16:01-*05:02, *14:01-4-*05:03 are protective for multiple sclerosis (MS), while *13:03-*03:01, *04:05-*03:01, *03:01-*02:01, *15:01-*06:02 and Mycobacterium avium subspecies paratubercolosis (MAP) are predisposing facto...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0669-1
更新日期:2016-08-23 00:00:00
abstract:BACKGROUND:Complications after stroke have been associated with poor outcome. Modern stroke treatment might reduce the occurrence of complications. The aim of this study was to investigate whether the frequency and type of complications during the first week after stroke has changed in patients treated in a stroke unit...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0654-8
更新日期:2016-08-11 00:00:00
abstract:BACKGROUND:Hemifacial spasm (HFS) is a disabling neurological condition. Vascular tortuosity in HFS patients has not been quantified objectively and its relationship with hypertension and posterior fossa volume (PF) is unknown. In a case control magnetic resonance imaging and angiographic (MRI/A) study, we quantified a...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0634-z
更新日期:2016-07-29 00:00:00
abstract:BACKGROUND:Volume isotropic turbo spin-echo acquisition (VISTA) is a new method similar to the 3D black-blood imaging method that enables visualization of a intramural hematoma. T1-VISTA has recently been applied in the diagnosis of intracranial arterial dissection. However, the identification of an intramural hematoma...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0637-9
更新日期:2016-07-29 00:00:00
abstract:BACKGROUND:This study aimed to determine the risk of thromboembolic events in patients with junctional bradycardia(JB). METHODS:We retrospectively reviewed electrocardiograms(ECGs) for 380,682 patients. Those with JB on an ECG at least twice over a ≥3-month interval were included for analysis. We additionally included...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0645-9
更新日期:2016-07-25 00:00:00
abstract:BACKGROUND:Rett syndrome is a severe neurodevelopmental disorder that primarily affects females. Typical features include a loss of purposeful hand skills, development of hand stereotypies, loss of spoken language, gait abnormalities, and acquired microcephaly. However, Rett syndrome hasn't been recognized by clinical ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0613-4
更新日期:2016-06-13 00:00:00
abstract:BACKGROUND:This multicenter, double-blind, placebo-controlled study assessed the efficacy of rotigotine transdermal patch on apathy and motor symptoms in patients with Parkinson's disease (PD). METHODS:Patients with PD-associated apathy (Unified Parkinson's Disease Rating Scale [UPDRS] I item 4 [motivation] ≥2 and pat...
journal_title:BMC neurology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/s12883-016-0610-7
更新日期:2016-06-07 00:00:00
abstract:BACKGROUND:Reversible splenial lesion syndrome (RESLES) is a disorder radiologically characterized by reversible lesion in the splenium of the corpus callosum (SCC). Most of patients with RESLES associated with encephalitis/encephalopathy were identified in Japanese population, but almost no Chinese patients were diagn...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0572-9
更新日期:2016-04-18 00:00:00
abstract::Leakage of the blood-brain barrier (BBB) is a common pathological feature in multiple sclerosis (MS). Following a breach of the BBB, albumin, the most abundant protein in plasma, gains access to CNS tissue where it is exposed to an inflammatory milieu and tissue damage, e.g., demyelination. Once in the CNS, albumin ca...
journal_title:BMC neurology
pub_type: 杂志文章,评审
doi:10.1186/s12883-016-0564-9
更新日期:2016-04-12 00:00:00
abstract:BACKGROUND:The production of inflammatory cytokines resulting from amyloid β (Aβ) is associated with the initiation of Alzheimer's disease (AD). Atorvastatin (ATV) has been reported to improve AD, however, it is unclear how the anti-inflammatory mechanism is linked with its protection against the impairment of spatial ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-016-0533-3
更新日期:2016-02-04 00:00:00
abstract::The term paraproteinemic neuropathy describes a heterogeneous set of neuropathies characterized by the presence of homogeneous immunoglobulin in the serum. An abnormal clonal proliferation of B-lymphocytes or plasma cells, which may or may not occur in the context of a hematologic malignancy, produces the immunoglobul...
journal_title:BMC neurology
pub_type: 杂志文章,评审
doi:10.1186/s12883-016-0532-4
更新日期:2016-01-28 00:00:00
abstract:BACKGROUND:Stroke survivors encounter emotional problems in the chronic phase after stroke. Post-stroke depressive symptoms have major impact on health-related quality of life (HRQol) and lead to increased hospitalization and therefore substantial healthcare costs. We present a cost-effectiveness and cost-utility evalu...
journal_title:BMC neurology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/s12883-015-0522-y
更新日期:2015-12-29 00:00:00
abstract:BACKGROUND:Muscular weakness in myasthenia gravis (MG) is commonly assessed using Quantitative Myasthenia Gravis Score (QMG). More objective and quantitative measures may complement the use of clinical scales and might detect subclinical affection of muscles. We hypothesized that muscular weakness in patients with MG c...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0517-8
更新日期:2015-12-23 00:00:00
abstract:BACKGROUND:Parkinson's disease, the second most common neurodegenerative disease, is diagnostically defined by motor impairments, but also includes often under-recognized impairments in cognition, mood, sleep, and the autonomic nervous system. These problems can severely affect individuals' quality of life. In our prio...
journal_title:BMC neurology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12883-015-0506-y
更新日期:2015-12-15 00:00:00
abstract:BACKGROUND:The etiologic determinants of stroke in young adults remain a diagnostic challenge in up to one-fourth of cases. Increasing evidences led to consider Fabry's disease (FD) as a possible cause to check up. We aimed at evaluating the prevalence of unrecognized FD in a cohort of patients with juvenile stroke in ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0513-z
更新日期:2015-12-12 00:00:00
abstract:BACKGROUND:An Early Supported Discharge (ESD) and rehabilitation from a coordinated team in the home environment is recommended in several high-income countries for patients with mild to moderate symptoms after stroke. Returning home from the hospital takes place very early in Sweden today (12 days post stroke), thus t...
journal_title:BMC neurology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12883-015-0492-0
更新日期:2015-11-16 00:00:00
abstract:BACKGROUND:"Anarchic hand" is a rare condition characterised by non-volitional, goal-directed movements of one arm. We report a case with analysis of structural and functional connectivity. CASE PRESENTATION:A 15 year old girl developed intermittent symptoms of intermanual conflict or anarchic hand as a result of trau...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0477-z
更新日期:2015-11-14 00:00:00
abstract:BACKGROUND:Several studies suggest that perceived psychosocial stress is associated with increased risk of stroke; however results are inconsistent with regard to definitions and measurement of perceived stress, features of individual study design, study conduct and conclusions drawn and no meta-analysis has yet been p...
journal_title:BMC neurology
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12883-015-0456-4
更新日期:2015-11-12 00:00:00
abstract:BACKGROUND:Different apoptosis pathways activate caspase-3. In a study involving 27 patients with traumatic brain injury (TBI), higher caspase-3 levels were found in contusion brain tissue resected from non-survivors than from survivors. The objective of this study was to determine whether there is an association in TB...
journal_title:BMC neurology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12883-015-0485-z
更新日期:2015-11-06 00:00:00
abstract:BACKGROUND:Cerebral microvascular abnormality is frequently associated with lacunar and subcortical ischemic lesions. We performed acute and follow-up CT perfusion scans over the first 3 months after ischemic stroke to investigate disturbances of the blood-brain barrier (BBB) and cerebral perfusion in patients with lac...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0468-0
更新日期:2015-10-22 00:00:00
abstract:BACKGROUND:Mixed pathology, particularly Alzheimer's disease with cerebrovascular lesions, is reported as the second most common cause of dementia. Research on mixed dementia typically includes people with a primary AD diagnosis and hence, little is known about the effects of co-existing amyloid pathology in people wit...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0459-1
更新日期:2015-10-12 00:00:00
abstract:BACKGROUND:Falls frequency increases with age and particularly in neurogeriatric cohorts. The interplay between eye movements and locomotion may contribute substantially to the occurrence of falls, but is hardly investigated. This paper provides an overview of current approaches to simultaneously measure eye and body m...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0447-5
更新日期:2015-10-09 00:00:00
abstract:BACKGROUND:Acute seizures are a common cause of paediatric admissions to hospitals in Africa, and malaria is an important cause of seizures in endemic areas. Malaria has declined in the past decade whilst neonatal admissions have increased, both which may affect the incidence and phenotypes of acute seizures in African...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0444-8
更新日期:2015-10-06 00:00:00
abstract:BACKGROUND:In the pathogenesis of limbic encephalitis other promoting factors besides the pure existence of autoantibodies are increasingly discussed to play a significant role. This is to our knowledge the first described patient in whom the presence of autoantibodies precedes the manifestation of limbic encephalitis ...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0435-9
更新日期:2015-09-30 00:00:00
abstract:BACKGROUND:Limb Girdle Muscular Dystrophy (LGMD), caused by defective α-dystroglycan (α-DG) glycosylation, was recently associated with mutations in Isoprenoid synthase domain-containing (ISPD) and GDP-mannose pyrophosphorylase B (GMPPB) genes. The frequency of ISPD and GMPPB gene mutations in the LGMD population is un...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0428-8
更新日期:2015-09-24 00:00:00
abstract:BACKGROUND:To evaluate the relationship between the flow signal intensity of branch arteries distal to the stenosis on 3-dimensional (3D) time-of-flight (TOF) magnetic resonance angiography (MRA) and the risk of stroke recurrence in patients with severe middle cerebral artery (MCA) trunk stenosis. METHODS:We prospecti...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0423-0
更新日期:2015-09-16 00:00:00
abstract:BACKGROUND:Association of leukoencephalopathy and atypical mycobacteriosis has been rarely reported. We present a case that is relevant for its unusual presentation and because it may shed further light on the pathogenic mechanisms underlying reversible encephalopathies. CASE REPORT:We report the case of a Hispanic 64...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0415-0
更新日期:2015-09-02 00:00:00
abstract:BACKGROUND:Patients often report neurocognitive difficulties after neuroborreliosis (NB). The frequency and extent of cognitive problems in European patients have been studied incompletely. METHODS:Sixty patients received a neurological and neuropsychological work-up 6 months or longer after treatment for proven NB. Q...
journal_title:BMC neurology
pub_type: 杂志文章
doi:10.1186/s12883-015-0386-1
更新日期:2015-08-19 00:00:00